| Date | Location | Result | |
| 02-26-11 | Canton, N.Y.; Burkman Gymnasium | Vassar 77, William Smith 67 | Box score |
| 02-25-11 | Canton, N.Y.; Burkman Gymnasium | William Smith 76, Union (N.Y.) 64 | Box score |
| 02-19-11 | Geneva, N.Y.; Bristol Gym | William Smith 84, Vassar 73 | Box score |
| 02-18-11 | Geneva, N.Y.; Bristol Gym | William Smith 72, Rensselaer 64 | Box score |
| 02-12-11 | Canton, N.Y.; Burkman Gymnasium | William Smith 81, St. Lawrence 76 | Box score |
| 02-11-11 | Potsdam, NY; Alumni Gymnasium | William Smith 67, Clarkson 59 | Box score |
| 02-08-11 | Clinton, N.Y.; Scott Field House | William Smith 67, Hamilton 53 | Box score |
| 02-05-11 | Saratoga Springs, NY; Williamson Center | Skidmore 56, William Smith 49 | Box score |
| 02-04-11 | Schenectady, N.Y.; Viniar Athletic Centr | William Smith 71, Union (N.Y.) 55 | Box score |
| 01-29-11 | Geneva, N.Y.; Bristol Gym | William Smith 61, Clarkson 51 | Box score |
| 01-28-11 | Geneva, N.Y.; Bristol Gym | St. Lawrence 78, William Smith 75 | Box score |
| 01-22-11 | Troy, N.Y.; East Campus Arena | William Smith 67, Rensselaer 60 | Box score |
| 01-21-11 | Poughkeepsie, N.Y.; (AFC) | William Smith 66, Vassar 57 | Box score |
| 01-15-11 | Geneva, N.Y.; Bristol Gym | Union (N.Y.) 74, William Smith 72 | Box score |
| 01-14-11 | Geneva, N.Y.; Bristol Gym | Skidmore 88, William Smith 82 | Box score |
| 01-10-11 | Geneva, N.Y.; Bristol Gym | William Smith 74, Hamilton 52 | Box score |
| 01-04-11 | Geneva, N.Y.; Bristol Gym | William Smith 86, Potsdam St. 44 | Box score |
| 12-30-10 | Buffalo, N.Y.; Sullivan Center | Medaille 79, William Smith 72 | Box score |
| 12-18-10 | Geneva, N.Y.; Bristol Gym | William Smith 72, Cortland St. 70 | Box score |
| 12-10-11 | Rochester, N.Y.; Palestra | Rochester (N.Y.) 74, William Smith 51 | Box score |
| 12-09-10 | Keuka Park, N.Y.; Weed Phys. Arts Center | Keuka 72, William Smith 67 | Box score |
| 12-04-10 | Rochester, N.Y.; Voller Athletic Center | William Smith 64, Geneseo St. 59 | Box score |
| 12-02-10 | Rochester, N.Y.; Roberts Wesleyan | Rochester (N.Y.) 85, William Smith 51 | Box score |
| 11-30-10 | Geneseo, N.Y. | William Smith 73, Brockport State 49 | Box score |
| 11-21-10 | Boston, Mass.; Jean Yawkey Center | William Smith 90, Staten Island 57 | Box score |
| 11-20-10 | Boston, Mass.; Yawkey Center | Williams 72, William Smith 55 | Box score |
| 11-16-10 | Ithaca, N.Y.; Ben Light Gymnasium | Ithaca 78, William Smith 64 | Box score |